Lenalidomide-C4-NH2 hydrochloride | E3 ligase Ligand-Linker Conjugates 32 hydrochloride | Cereblon ligand 1 hydrochloride | AnyMole

有库存

HIT212080469

sdf 文件

结构编辑

类似物检索

HIT212080469

HIT ID:HIT212080469
Cas No:
常用名:Lenalidomide-C4-NH2 hydrochloride
常用名:Lenalidomide-C4-NH2 hydrochloride
别名:E3 ligase Ligand-Linker Conjugates 32 hydrochloride, Cereblon ligand 1 hydrochloride
别名:E3 ligase Ligand-Linker Conjugates 32 hydrochloride, Cereblon ligand 1 hydrochloride
IUPAC:3-[4-(4-aminobutyl)-1-oxo-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione hydrochloride
IUPAC:3-[4-(4-aminobutyl)-1-oxo-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione hydrochloride
InChI key:QPGHLNCBGNJWKG-UHFFFAOYSA-N

分子式:C17H22ClN3O3
分子量:351.83
氢键供体数 (HBD):2
氢键受体数 (HBA):4
LogP:0.26682267
SMILES:Cl.NCCCCc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O
SMILES:Cl.NCCCCc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O

Lenalidomide-C4-NH2 hydrochloride is a Cereblon ligand derived from Lenalidomide. It serves as a recruiting agent for the CRBN protein. The compound, known as PROTAC (Compound 24), can be formed by linking Lenalidomide-C4-NH2 hydrochloride to the ligand for the protein. It exhibits inhibitory effects with IC50s of 0.98 nM and 13.7 nM against the growth of RS4;11 and MOLM-13 acute leukemia cell lines, respectively[1].

市场产品/服务共显示1个结果

供应商
TargetMolSC
规格
货期
5日内发货
纯度
-
¥ 482.00
1

寻找合适的化合物库

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

TargetMol | Target Loading

正在加载 ~