S-Acetyl-PEG8-OH | CAS 1334177-81-9 | AnyMole

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HIT212080622

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HIT212080622

HIT ID:HIT212080622
Cas No:1334177-81-9
常用名:S-Acetyl-PEG8-OH
IUPAC:1-hydroxy-3,6,9,12,15,18,21-heptaoxa-24-thiahexacosan-25-one
IUPAC:1-hydroxy-3,6,9,12,15,18,21-heptaoxa-24-thiahexacosan-25-one
InChI key:PGTIAXGQNCASCI-UHFFFAOYSA-N

分子式:C18H36O9S
分子量:428.54
氢键供体数 (HBD):1
氢键受体数 (HBA):9
LogP:-1.75
SMILES:CC(=O)SCCOCCOCCOCCOCCOCCOCCOCCO
SMILES:CC(=O)SCCOCCOCCOCCOCCOCCOCCOCCO

S-Acetyl-PEG8-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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