Name: Azido-PEG8-NHS ester
Rating: 5 (10 reviews)

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HIT ID:HIT212080694
Cas No:1204834-00-3
常用名:Azido-PEG8-NHS ester
IUPAC:2,5-dioxopyrrolidin-1-yl 1-azido-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
IUPAC:2,5-dioxopyrrolidin-1-yl 1-azido-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate
InChI key:AZXJVYAMFTUKFC-UHFFFAOYSA-N

分子式:C23H40N4O12
分子量:564.589
氢键供体数 (HBD):0
氢键受体数 (HBA):12
LogP:-3.68
SMILES:[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
SMILES:[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O

Azido-PEG8-NHS ester is an 8 unit PEG linker with cleavable properties, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1]. This compound also serves as a PEG- and Alkyl/ether-based PROTAC linker, enabling its utilization in the synthesis of PROTACs[2].

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