Name: m-PEG24-azide
Rating: 5 (10 reviews)

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HIT ID:HIT212080705
Cas No:
常用名:m-PEG24-azide
IUPAC:73-azido-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71-tetracosaoxatriheptacontane
IUPAC:73-azido-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71-tetracosaoxatriheptacontane
InChI key:UZZSJVSWGGAHCH-UHFFFAOYSA-N

分子式:C49H99N3O24
分子量:1114.328
氢键供体数 (HBD):0
氢键受体数 (HBA):24
LogP:-4.28
SMILES:COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
SMILES:COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

m-PEG24-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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