Name: Tos-PEG4-THP
Rating: 5 (10 reviews)

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HIT ID:HIT212091275
Cas No:86259-89-4
常用名:Tos-PEG4-THP
IUPAC:2-(2-{2-[2-(oxan-2-yloxy)ethoxy]ethoxy}ethoxy)ethyl 4-methylbenzene-1-sulfonate
IUPAC:2-(2-{2-[2-(oxan-2-yloxy)ethoxy]ethoxy}ethoxy)ethyl 4-methylbenzene-1-sulfonate
InChI key:AWIUPDGEVFBSGD-UHFFFAOYSA-N

分子式:C20H32O8S
分子量:432.53
氢键供体数 (HBD):0
氢键受体数 (HBA):7
LogP:2.7582
SMILES:Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOC1CCCCO1
SMILES:Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOC1CCCCO1

Tos-PEG4-THP is a polyethylene glycol (PEG) derivative utilized as a linker in the synthesis of PROTAC K-Ras Degrader-1, a potential therapeutic compound for targeted degradation of K-Ras protein [1].

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