Name: Hydroxy-PEG4-O-Boc
Rating: 5 (10 reviews)

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HIT ID:HIT212091276
Cas No:1807530-05-7
常用名:Hydroxy-PEG4-O-Boc
IUPAC:tert-butyl 17-hydroxy-3,6,9,12,15-pentaoxaheptadecanoate
IUPAC:tert-butyl 17-hydroxy-3,6,9,12,15-pentaoxaheptadecanoate
InChI key:XPLBSNFHNMATJJ-UHFFFAOYSA-N

分子式:C16H32O8
分子量:352.424
氢键供体数 (HBD):1
氢键受体数 (HBA):7
LogP:-0.0756176
SMILES:CC(C)(C)OC(=O)COCCOCCOCCOCCOCCO
SMILES:CC(C)(C)OC(=O)COCCOCCOCCOCCOCCO

Hydroxy-PEG4-O-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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