Name: Azide-PEG3-Tos
Rating: 5 (10 reviews)

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HIT ID:HIT212091279
Cas No:178685-33-1
常用名:Azide-PEG3-Tos
IUPAC:1-({2-[2-(2-azidoethoxy)ethoxy]ethoxy}sulfonyl)-4-methylbenzene
IUPAC:1-({2-[2-(2-azidoethoxy)ethoxy]ethoxy}sulfonyl)-4-methylbenzene
InChI key:PTOJCKLTCKYNFG-UHFFFAOYSA-N

分子式:C13H19N3O5S
分子量:329.37
氢键供体数 (HBD):0
氢键受体数 (HBA):6
LogP:2.081826
SMILES:Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCN=[N+]=[N-]
SMILES:Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCN=[N+]=[N-]

Azide-PEG3-Tos is a PEG-based PROTAC linker utilized in the synthesis of PROTACs[1]. It is a non-cleavable 3 unit PEG ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[2].

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