Name: Azido-PEG4-C2-acid
Rating: 5 (10 reviews)

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HIT ID:HIT212100386
Cas No:1257063-35-6
常用名:Azido-PEG4-C2-acid
IUPAC:1-azido-3,6,9,12-tetraoxapentadecan-15-oic acid
IUPAC:1-azido-3,6,9,12-tetraoxapentadecan-15-oic acid
InChI key:BODPHGOBXPGJKO-UHFFFAOYSA-N

分子式:C11H21N3O6
分子量:291.304
氢键供体数 (HBD):1
氢键受体数 (HBA):6
LogP:-3.37
SMILES:OC(=O)CCOCCOCCOCCOCCN=[N+]=[N-]
SMILES:OC(=O)CCOCCOCCOCCOCCN=[N+]=[N-]

Azido-PEG4-C2-acid, a PEG-based PROTAC linker, is utilized in the synthesis of vRucaparib-TP4. It serves as a non-cleavable 4 unit PEG ADC linker for antibody-drug conjugate (ADC) synthesis.

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