Name: K-252c
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212101398
Cas No:85753-43-1
常用名:K-252c
IUPAC:3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaen-12-one
IUPAC:3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tricosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaen-12-one
InChI key:MEXUTNIFSHFQRG-UHFFFAOYSA-N

分子式:C20H13N3O
分子量:311.344
氢键供体数 (HBD):3
氢键受体数 (HBA):1
LogP:3.0340693
SMILES:O=C1NCc2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21
SMILES:O=C1NCc2c1c1c3ccccc3[nH]c1c1[nH]c3ccccc3c21

K-252c is a staurosporine analog isolated from Nocardiopsis sp. and is a cell-permeable PKC inhibitor (IC50: 2.45 μM). K-252c also inhibits β-lactamase, chymotrypsin, and malate dehydrogenase. K-252c causes apoptosis in human chronic myelogenous leukemia cancer cells.

市场产品/服务共显示3个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~