Name: EPZ020411 HCl
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212651136
Cas No:2095432-47-4;2070015-25-5
常用名:EPZ020411 HCl
IUPAC:methyl[2-(methylamino)ethyl][(3-{4-[(1r,3r)-3-[2-(oxan-4-yl)ethoxy]cyclobutoxy]phenyl}-1H-pyrazol-4-yl)methyl]amine dihydrochloride
IUPAC:methyl[2-(methylamino)ethyl][(3-{4-[(1r,3r)-3-[2-(oxan-4-yl)ethoxy]cyclobutoxy]phenyl}-1H-pyrazol-4-yl)methyl]amine dihydrochloride
InChI key:QCHZLIPYCYHFLI-PZPNUJOOSA-N

分子式:C25H40Cl2N4O3
分子量:515.52
氢键供体数 (HBD):2
氢键受体数 (HBA):6
LogP:2.5391824
SMILES:Cl.Cl.CNCCN(C)Cc1c[nH]nc1-c1ccc(O[C@H]2C[C@@H](C2)OCCC2CCOCC2)cc1
SMILES:Cl.Cl.CNCCN(C)Cc1c[nH]nc1-c1ccc(O[C@H]2C[C@@H](C2)OCCC2CCOCC2)cc1

EPZ020411 is a potent and selective PRMT6 inhibitor tool compound. EPZ020411 shows good bioavailability following subcutaneous dosing in rats making it a suitable tool for in vivo studies. EPZ020411 suppresses RCC1 arginine methylation and improves the cytotoxic activity of radiotherapy against GSC brain tumor xenografts.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~