Lipopolysaccharides | 脂多糖 | LPS

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HIT ID:HIT212653996
Cas No:
常用名:Lipopolysaccharides
别名:脂多糖, LPS
IUPAC:(2R,5R)-5-{[(2R,3R,5R)-5-[({[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl)oxy]-4-{[(2R,3R,5R)-4-{[(2R,5R)-4-{[(2R,5R)-3-{[(2R,5S)-5-{[(2R,5S)-4-{[(3R,6S)-5-{[(2R,5R)-4-{[(2R,5R)-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-(hydroxymethyl)-3-{[(2R,5R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-3,4-dihydroxy-6-methyloxan-2-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3-{[(2R,3S,5S)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,5-dihydroxy-6-({[(2S,5R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-6-(2-{[(2S,3R,5S)-5-(1,2-dihydroxyethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-1-hydroxyethyl)-3-hydroxy-5-(phosphonooxy)oxan-2-yl]oxy}-6-(1,2-dihydroxyethyl)-3-hydroxyoxan-2-yl]oxy}-4-{[(2R,5R)-2-carboxy-4-{[(2R,5R)-2-carboxy-6-(1,2-dihydroxyethyl)-4,5-dihydroxyoxan-2-yl]oxy}-6-(1,2-dihydroxyethyl)-5-hydroxyoxan-2-yl]oxy}-6-(1,2-dihydroxyethyl)-2-{[(3S,5S,6R)-5-[3-(dodecanoyloxy)tetradecanamido]-6-{[(3S,4R,6S)-3-hydroxy-4-[(3-hydroxytetradecanoyl)oxy]-5-pentadecyl-6-(phosphonomethyl)oxan-2-yl]methoxy}-3-(phosphonooxy)-4-{[3-(tetradecanoyloxy)tetradecanoyl]oxy}oxan-2-yl]methoxy}oxane-2-carboxylic acid
IUPAC:(2R,5R)-5-{[(2R,3R,5R)-5-[({[(2-aminoethoxy)(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl)oxy]-4-{[(2R,3R,5R)-4-{[(2R,5R)-4-{[(2R,5R)-3-{[(2R,5S)-5-{[(2R,5S)-4-{[(3R,6S)-5-{[(2R,5R)-4-{[(2R,5R)-3,5-dihydroxy-6-methyloxan-2-yl]oxy}-5-hydroxy-6-(hydroxymethyl)-3-{[(2R,5R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}oxan-2-yl]oxy}-3,4-dihydroxy-6-methyloxan-2-yl]oxy}-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3-{[(2R,3S,5S)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-3,5-dihydroxy-6-({[(2S,5R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-6-(2-{[(2S,3R,5S)-5-(1,2-dihydroxyethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-1-hydroxyethyl)-3-hydroxy-5-(phosphonooxy)oxan-2-yl]oxy}-6-(1,2-dihydroxyethyl)-3-hydroxyoxan-2-yl]oxy}-4-{[(2R,5R)-2-carboxy-4-{[(2R,5R)-2-carboxy-6-(1,2-dihydroxyethyl)-4,5-dihydroxyoxan-2-yl]oxy}-6-(1,2-dihydroxyethyl)-5-hydroxyoxan-2-yl]oxy}-6-(1,2-dihydroxyethyl)-2-{[(3S,5S,6R)-5-[3-(dodecanoyloxy)tetradecanamido]-6-{[(3S,4R,6S)-3-hydroxy-4-[(3-hydroxytetradecanoyl)oxy]-5-pentadecyl-6-(phosphonomethyl)oxan-2-yl]methoxy}-3-(phosphonooxy)-4-{[3-(tetradecanoyloxy)tetradecanoyl]oxy}oxan-2-yl]methoxy}oxane-2-carboxylic acid
InChI key:YPXVSQSYDIMPDZ-RPTNFTJRSA-N

分子式:C205H366N3O117P5
分子量:4899.956
氢键供体数 (HBD):62
氢键受体数 (HBA):109
LogP:-6.151415
SMILES:CCCCCCCCCCCCCCCC1[C@@H](CP(O)(O)=O)OC(CO[C@@H]2OC(CO[C@@]3(CC(O[C@@]4(CC(O[C@@]5(CC(O)[C@@H](O)C(O5)C(O)CO)C(O)=O)[C@@H](O)C(O4)C(O)CO)C(O)=O)[C@@H](O[C@@H]4OC(C(O)CO)[C@@H](OP(O)(=O)OP(O)(=O)OCCN)C(O[C@H]5OC(C(O)CO[C@H]6OC[C@](O)(C(O)CO)C(O)[C@H]6O)[C@@H](OP(O)(O)=O)C(O[C@H]6OC(CO[C@H]7OC(CO)[C@H](O)C(O)C7O)[C@@H](O)C(O[C@H]7OC(CO)[C@H](O)C(O)C7O[C@H]7OC(CO)[C@@H](O[C@H]8OC(CO)[C@H](O)C(OC9O[C@@H](C)C(O[C@H]%10OC(CO)[C@@H](O)C(O[C@H]%11OC(C)[C@H](O)CC%11O)C%10O[C@H]%10OC(CO)[C@H](O)C(O)C%10O)C(O)[C@H]9O)C8O)C(O)C7O[C@H]7OC(CO)[C@@H](O)C(O)[C@@H]7NC(C)=O)C6O)[C@H]5O)[C@H]4O)C(O3)C(O)CO)C(O)=O)[C@@H](OP(O)(O)=O)C(OC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H]2NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H](O)[C@@H]1OC(=O)CC(O)CCCCCCCCCCC
SMILES:CCCCCCCCCCCCCCCC1[C@@H](CP(O)(O)=O)OC(CO[C@@H]2OC(CO[C@@]3(CC(O[C@@]4(CC(O[C@@]5(CC(O)[C@@H](O)C(O5)C(O)CO)C(O)=O)[C@@H](O)C(O4)C(O)CO)C(O)=O)[C@@H](O[C@@H]4OC(C(O)CO)[C@@H](OP(O)(=O)OP(O)(=O)OCCN)C(O[C@H]5OC(C(O)CO[C@H]6OC[C@](O)(C(O)CO)C(O)[C@H]6O)[C@@H](OP(O)(O)=O)C(O[C@H]6OC(CO[C@H]7OC(CO)[C@H](O)C(O)C7O)[C@@H](O)C(O[C@H]7OC(CO)[C@H](O)C(O)C7O[C@H]7OC(CO)[C@@H](O[C@H]8OC(CO)[C@H](O)C(OC9O[C@@H](C)C(O[C@H]%10OC(CO)[C@@H](O)C(O[C@H]%11OC(C)[C@H](O)CC%11O)C%10O[C@H]%10OC(CO)[C@H](O)C(O)C%10O)C(O)[C@H]9O)C8O)C(O)C7O[C@H]7OC(CO)[C@@H](O)C(O)[C@@H]7NC(C)=O)C6O)[C@H]5O)[C@H]4O)C(O3)C(O)CO)C(O)=O)[C@@H](OP(O)(O)=O)C(OC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)[C@@H]2NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)[C@@H](O)[C@@H]1OC(=O)CC(O)CCCCCCCCCCC

Lipopolysaccharides（LPS）来源于大肠杆菌O55:B5，是革兰氏阴性菌外膜的重要成分，由脂质A、核心寡糖和O-特异性多糖组成，具有高免疫原性，能激活免疫细胞TLR4受体，诱导细胞迁移体分泌，并有助于维持细菌外膜完整性、抵御胆汁盐和脂类抗生素的破坏，常用于炎症模型的构建，如关节炎、慢性阻塞性肺病（COPD）、急性呼吸窘迫综合征（ARDS）、以及消化系统等疾病模型的构建。

市场产品/服务共显示1个结果

供应商
TargetMolSC
规格
货期
1-3天
纯度
-
¥ 449.00
1

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