R715 TFA(185052-09-9 free base) | R 715

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212661489
Cas No:
常用名:R715 TFA(185052-09-9 free base)
别名:R 715
IUPAC:(2S,3S)-2-[(2R)-2-[(2S)-2-[(2S)-2-(2-{[(2S)-1-[(2S)-1-[(2S)-2-[(2S)-6-amino-2-acetamidohexanamido]-5-[(diaminomethylidene)amino]pentanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl]formamido}acetamido)-3-phenylpropanamido]-3-hydroxypropanamido]-3-(naphthalen-2-yl)propanamido]-3-methylpentanoic acid; trifluoroacetic acid
IUPAC:(2S,3S)-2-[(2R)-2-[(2S)-2-[(2S)-2-(2-{[(2S)-1-[(2S)-1-[(2S)-2-[(2S)-6-amino-2-acetamidohexanamido]-5-[(diaminomethylidene)amino]pentanoyl]pyrrolidine-2-carbonyl]pyrrolidin-2-yl]formamido}acetamido)-3-phenylpropanamido]-3-hydroxypropanamido]-3-(naphthalen-2-yl)propanamido]-3-methylpentanoic acid; trifluoroacetic acid
InChI key:ZFUJDXXJCMFOSK-WBUMRSSGSA-N

分子式:C59H82F3N13O14
分子量:1254.377
氢键供体数 (HBD):12
氢键受体数 (HBA):16
LogP:-3.6887746
SMILES:[#8]-[#6](=O)C(F)(F)F.[#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-c1ccc2ccccc2c1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](-[#6])=O)-[#6](-[#8])=O
SMILES:[#8]-[#6](=O)C(F)(F)F.[#6]-[#6]-[#6@H](-[#6])-[#6@H](-[#7]-[#6](=O)-[#6@@H](-[#6]-c1ccc2ccccc2c1)-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#7]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#7]-[#6](-[#6])=O)-[#6](-[#8])=O

R715 TFA(185052-09-9 free base) 是强效和选择性缓激肽 B1 受体拮抗剂 (pA2 = 8.49)。它对B2 受体无活性。它减少神经性疼痛小鼠模型中的机械性过度伤害感受。它代谢稳定。

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~