Name: 8-Prenylkaempferol
Rating: 5 (10 reviews)

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HIT ID:HIT212665236
Cas No:28610-31-3
常用名:8-Prenylkaempferol
别名:去甲脱水淫羊藿黄素
IUPAC:3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one
IUPAC:3,5,7-trihydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-4H-chromen-4-one
InChI key:NADCVNHITZNGJU-UHFFFAOYSA-N

分子式:C20H18O6
分子量:354.358
氢键供体数 (HBD):4
氢键受体数 (HBA):6
LogP:4.1884317
SMILES:[#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc(-[#8])c2c1oc(-c1ccc(-[#8])cc1)c(-[#8])c2=O
SMILES:[#6]\[#6](-[#6])=[#6]\[#6]-c1c(-[#8])cc(-[#8])c2c1oc(-c1ccc(-[#8])cc1)c(-[#8])c2=O

8-Prenylkaempferol is an effective agent for attenuating pro-inflammatory NO induction, it may be an anti-inflammatory agent for suppressing influenza A virus-induced RANTES production acts by blocking PI3K-mediated transcriptional activation of NF-κB and IRF-3 and in part by interfering with IκB degradation which subsequently decreases NF-κB translocation.

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