Name: Corydalmine
Rating: 5 (10 reviews)

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HIT ID:HIT212665377
Cas No:30413-84-4
常用名:Corydalmine
别名:紫堇达明碱
IUPAC:(12bS)-4,10,11-trimethoxy-7,8,12b,13-tetrahydro-5H-6-azatetraphen-3-ol
IUPAC:(12bS)-4,10,11-trimethoxy-7,8,12b,13-tetrahydro-5H-6-azatetraphen-3-ol
InChI key:DIHXHTWYVOYYDC-INIZCTEOSA-N

分子式:C20H23NO4
分子量:341.407
氢键供体数 (HBD):1
氢键受体数 (HBA):5
LogP:3.0020807
SMILES:COc1cc2CCN3Cc4c(C[C@H]3c2cc1OC)ccc(O)c4OC
SMILES:COc1cc2CCN3Cc4c(C[C@H]3c2cc1OC)ccc(O)c4OC

Corydalmine exhibits antibacterial activities against Staphylococcus aureus and methicillin-resistant S. aureus strains.1-Corydalmine significantly inhibits spore germination of all the fungi at 100 to 1500 ppm. l-Corydalmine also exhibits potent analgesic activity in preclinical models, it is under development as an oral analgesic agent.

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