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HIT212665507
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HIT212665507
  • HIT ID:HIT212665507
  • Cas No:60008-03-9
  • 常用名:Glabrene
  • 别名:光甘草素
  • IUPAC:2',2'-dimethyl-2H,2'H-[3,8'-bichromene]-5',7-diol
    IUPAC:2',2'-dimethyl-2H,2'H-[3,8'-bichromene]-5',7-diol
  • InChI key:NGGYSPUAKQMTNP-UHFFFAOYSA-N
  • 分子式:C20H18O4
  • 分子量:322.36
  • 氢键供体数 (HBD):2
  • 氢键受体数 (HBA):4
  • LogP:3.9861088
  • SMILES:CC1(C)Oc2c(ccc(O)c2C=C1)C1=Cc2ccc(O)cc2OC1 |c:12,t:15|
    SMILES:CC1(C)Oc2c(ccc(O)c2C=C1)C1=Cc2ccc(O)cc2OC1 |c:12,t:15|
  • Glabrene, Liquiritin apioside, neolicuroside, and 18α2-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely the major contributors to the notable synergistic antioxidant activity when coupled with pea protein hydrolysates (PPHs).Glabrene has estrogen-like activity, it can stimulate DNA synthesis in human endothelial cells (ECV-304; E304) and has a bi-phasic effect on proliferation of human vascular smooth muscle cells (VSMC). Glabrene and isoliquiritigenin may serve as candidates for skin-lightening agents, they exert varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis.
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    AnyMoleSC
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