Name: (+)-Medioresinol
Rating: 5 (10 reviews)

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HIT ID:HIT212665683
Cas No:40957-99-1;74465-40-0
常用名:(+)-Medioresinol
别名:皮树脂醇, 梣皮树脂醇, Medioresinol
IUPAC:4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-3-methoxyphenyl)-hexahydrofuro[3,4-c]furan-1-yl]-2,6-dimethoxyphenol
IUPAC:4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-3-methoxyphenyl)-hexahydrofuro[3,4-c]furan-1-yl]-2,6-dimethoxyphenol
InChI key:VJOBNGRIBLNUKN-BMHXQBNDSA-N

分子式:C21H24O7
分子量:388.416
氢键供体数 (HBD):2
氢键受体数 (HBA):7
LogP:2.1200883
SMILES:[H][C@]12CO[C@H](c3cc(OC)c(O)c(OC)c3)[C@@]1([H])CO[C@@H]2c1ccc(O)c(OC)c1
SMILES:[H][C@]12CO[C@H](c3cc(OC)c(O)c(OC)c3)[C@@]1([H])CO[C@@H]2c1ccc(O)c(OC)c1

(+)-Medioresinol possesses antioxidative, a lesishmanicidal activity and cardiovascular disease risk reduction, it has antiamyloidogenic activity via reduction in the amount of α2-secretase, it is a potentially valuable antiamyloidogenic agent for the prevention and treatment of Alzheimer disease. (+)-Medioresinol has anti-bacterial, antifungal and anti-biofilm activities.

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