Name: MG-277
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212666046
Cas No:
常用名:MG-277
IUPAC:(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-N-{5-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]pentyl}-2''-oxo-1'',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indole]-5'-carboxamide
IUPAC:(3'R,4'S,5'R)-6''-chloro-4'-(3-chloro-2-fluorophenyl)-N-{5-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-2,3-dihydro-1H-isoindol-4-yl]pentyl}-2''-oxo-1'',2''-dihydrodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indole]-5'-carboxamide
InChI key:BANRYGZZIMCKNA-OYGJEQPESA-N

分子式:C41H42Cl2FN5O5
分子量:774.72
氢键供体数 (HBD):4
氢键受体数 (HBA):6
LogP:5.916394
SMILES:Fc1c(Cl)cccc1[C@H]1[C@@H](NC2(CCCCC2)[C@@]11C(=O)Nc2cc(Cl)ccc12)C(=O)NCCCCCc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O
SMILES:Fc1c(Cl)cccc1[C@H]1[C@@H](NC2(CCCCC2)[C@@]11C(=O)Nc2cc(Cl)ccc12)C(=O)NCCCCCc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O

MG-277 is a molecular glue compound transformed from PROTAC degradation agent, MG-277 potently inhibits tumor cell growth in a p53-independent manner.

市场产品/服务共显示2个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymol随时为您提供帮助。

电话：400-820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~