Name: ABT-546
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212666893
Cas No:212481-66-8
常用名:ABT-546
别名:A-216546
IUPAC:(2S,3R,4S)-1-[(dibutylcarbamoyl)methyl]-2-(2,2-dimethylpentyl)-4-(7-methoxy-2H-1,3-benzodioxol-5-yl)pyrrolidine-3-carboxylic acid
IUPAC:(2S,3R,4S)-1-[(dibutylcarbamoyl)methyl]-2-(2,2-dimethylpentyl)-4-(7-methoxy-2H-1,3-benzodioxol-5-yl)pyrrolidine-3-carboxylic acid
InChI key:OAEWNSKRLBVVBV-QSEAXJEQSA-N

分子式:C30H48N2O6
分子量:532.722
氢键供体数 (HBD):1
氢键受体数 (HBA):7
LogP:5.609
SMILES:CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CC(C)(C)CCC)C(O)=O)c1cc2OCOc2c(OC)c1
SMILES:CCCCN(CCCC)C(=O)CN1C[C@@H]([C@H]([C@@H]1CC(C)(C)CCC)C(O)=O)c1cc2OCOc2c(OC)c1

ABT-546 (A-216546) is a potent, highly selective, and active endothelin ETA receptor antagonist with a Ki of 0.46 nM for [125I]endothelin-1 binding to cloned human endothelin ETA.

市场产品/服务共显示2个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~