Name: CWHM-1008
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212666938
Cas No:2362539-97-5
常用名:CWHM-1008
IUPAC:(3R,4S)-N-[(1S)-1-[4-(dimethylamino)phenyl]ethyl]-4-[4-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide
IUPAC:(3R,4S)-N-[(1S)-1-[4-(dimethylamino)phenyl]ethyl]-4-[4-(trifluoromethyl)phenyl]pyrrolidine-3-carboxamide
InChI key:BNAUPWAOLQXQJZ-KPOBHBOGSA-N

分子式:C22H26F3N3O
分子量:405.465
氢键供体数 (HBD):2
氢键受体数 (HBA):3
LogP:3.6340218
SMILES:C[C@H](NC(=O)[C@H]1CNC[C@@H]1c1ccc(cc1)C(F)(F)F)c1ccc(cc1)N(C)C
SMILES:C[C@H](NC(=O)[C@H]1CNC[C@@H]1c1ccc(cc1)C(F)(F)F)c1ccc(cc1)N(C)C

CWHM-1008 is an effective oral antimalarial drug. The EC50 values of the drug-sensitive Plasmodium falciparum 3D7 and drug-resistant Dd2 strains are 46 and 21 nM, respectively.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~