Name: Azido-PEG16-acid
Rating: 5 (10 reviews)

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HIT ID:HIT212667363
Cas No:
常用名:Azido-PEG16-acid
别名:N3-PEG16-CH2CH2COOH
IUPAC:1-azido-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48-hexadecaoxahenpentacontan-51-oic acid
IUPAC:1-azido-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48-hexadecaoxahenpentacontan-51-oic acid
InChI key:QIBRWZBFMOLGLH-UHFFFAOYSA-N

分子式:C35H69N3O18
分子量:819.94
氢键供体数 (HBD):1
氢键受体数 (HBA):20
LogP:-0.73484474
SMILES:OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
SMILES:OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]

Azido-PEG16-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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