Name: Bis-propargyl-PEG13
Rating: 5 (10 reviews)

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HIT ID:HIT212667477
Cas No:
常用名:Bis-propargyl-PEG13
IUPAC:4,7,10,13,16,19,22,25,28,31,34,37,40,43-tetradecaoxahexatetraconta-1,45-diyne
IUPAC:4,7,10,13,16,19,22,25,28,31,34,37,40,43-tetradecaoxahexatetraconta-1,45-diyne
InChI key:CNZIDLBDXPTXEJ-UHFFFAOYSA-N

分子式:C32H58O14
分子量:666.802
氢键供体数 (HBD):0
氢键受体数 (HBA):14
LogP:-0.02996608
SMILES:C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C
SMILES:C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C

Bis-propargyl-PEG13 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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