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  3. HIT212667487
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HIT212667487
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HIT212667487
  • HIT ID:HIT212667487
  • Cas No:2381196-81-0
  • 常用名:Boc-C1-PEG3-C4-OBn
  • IUPAC:tert-butyl 1-phenyl-2,9,12,15-tetraoxaheptadecan-17-oate
    IUPAC:tert-butyl 1-phenyl-2,9,12,15-tetraoxaheptadecan-17-oate
  • InChI key:RBTVTEMDPRBJLY-UHFFFAOYSA-N
  • 分子式:C23H38O6
  • 分子量:410.551
  • 氢键供体数 (HBD):0
  • 氢键受体数 (HBA):5
  • LogP:3.8523927
  • SMILES:CC(C)(C)OC(=O)COCCOCCOCCCCCCOCc1ccccc1
    SMILES:CC(C)(C)OC(=O)COCCOCCOCCCCCCOCc1ccccc1
  • Boc-C1-PEG3-C4-OBn (PROTAC Linker 15) is a PEG-based PROTAC linker employed in the synthesis of various PROTACs, including PROTAC SGK3 degrader-1. PROTACs are composed of two distinct ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, while the other specifically interacts with the target protein. By leveraging the intracellular ubiquitin-proteasome system, PROTACs can selectively degrade target proteins[1].
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    TargetMolSC
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    ¥ 192.00
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