Name: Cbz-N-PEG15-amine
Rating: 5 (10 reviews)

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HIT ID:HIT212667535
Cas No:
常用名:Cbz-N-PEG15-amine
IUPAC:benzyl N-(47-amino-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxaheptatetracontan-1-yl)carbamate
IUPAC:benzyl N-(47-amino-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45-pentadecaoxaheptatetracontan-1-yl)carbamate
InChI key:HGHDEVQJEXSZRL-UHFFFAOYSA-N

分子式:C40H74N2O17
分子量:855.029
氢键供体数 (HBD):2
氢键受体数 (HBA):17
LogP:0.03553556
SMILES:NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCc1ccccc1
SMILES:NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)OCc1ccccc1

Cbz-N-PEG15-amine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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