Name: Nutlin-C1-amido-PEG4-C2-N3
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212667692
Cas No:
常用名:Nutlin-C1-amido-PEG4-C2-N3
别名:MDM2 Ligand-Linker Conjugates 1, E3 ligase Ligand-Linker Conjugates 48
别名:MDM2 Ligand-Linker Conjugates 1, E3 ligase Ligand-Linker Conjugates 48
IUPAC:N-(14-azido-3,6,9,12-tetraoxatetradecan-1-yl)-2-{4-[(4R,5S)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazole-1-carbonyl]-2-oxopiperazin-1-yl}acetamide
IUPAC:N-(14-azido-3,6,9,12-tetraoxatetradecan-1-yl)-2-{4-[(4R,5S)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazole-1-carbonyl]-2-oxopiperazin-1-yl}acetamide
InChI key:YLHONJUOEKAZKP-PVXQIPPMSA-N

分子式:C42H52Cl2N8O9
分子量:883.83
氢键供体数 (HBD):1
氢键受体数 (HBA):12
LogP:4.233325
SMILES:COc1ccc(C2=N[C@@H]([C@@H](N2C(=O)N2CCN(CC(=O)NCCOCCOCCOCCOCCN=[N+]=[N-])C(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1 |t:6|
SMILES:COc1ccc(C2=N[C@@H]([C@@H](N2C(=O)N2CCN(CC(=O)NCCOCCOCCOCCOCCN=[N+]=[N-])C(=O)C2)c2ccc(Cl)cc2)c2ccc(Cl)cc2)c(OC(C)C)c1 |t:6|

Nutlin-C1-amido-PEG4-C2-N3 is a novel compound that functions as a ligand-linker conjugate for the E3 ligase. It is a synthesized molecule incorporating the MDM2 ligand derived from Nutlin 3, and a 4-unit PEG linker. This compound is specifically designed for utilization in PROTAC technology.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~