Name: Gemcitabine-O-Si(di-iso)-O-Mc
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212667757
Cas No:
常用名:Gemcitabine-O-Si(di-iso)-O-Mc
IUPAC:1-{5-[({[(2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4,4-difluoro-3-hydroxyoxolan-2-yl]methoxy}bis(propan-2-yl)silyl)oxy]pentyl}-2,5-dihydro-1H-pyrrole-2,5-dione
IUPAC:1-{5-[({[(2R,3R,5R)-5-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-4,4-difluoro-3-hydroxyoxolan-2-yl]methoxy}bis(propan-2-yl)silyl)oxy]pentyl}-2,5-dihydro-1H-pyrrole-2,5-dione
InChI key:UANWPSOXUYWBLM-ZPMCFJSWSA-N

分子式:C24H36F2N4O7Si
分子量:558.655
氢键供体数 (HBD):2
氢键受体数 (HBA):9
LogP:2.4113
SMILES:CC(C)[Si](OCCCCCN1C(=O)C=CC1=O)(OC[C@H]1O[C@@H](n2ccc(N)nc2=O)C(F)(F)[C@@H]1O)C(C)C |c:13|
SMILES:CC(C)[Si](OCCCCCN1C(=O)C=CC1=O)(OC[C@H]1O[C@@H](n2ccc(N)nc2=O)C(F)(F)[C@@H]1O)C(C)C |c:13|

Gemcitabine-O-Si(di-iso)-O-Mc, a drug-linker conjugate for Antibody-Drug Conjugates (ADC), exhibits potent antitumor activity. It incorporates Gemcitabine, a pyrimidine nucleoside analog antimetabolite and antineoplastic agent, connected through the ADC linker[1].

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~