Name: HS-PEG10-CH2CH2COOH
Rating: 5 (10 reviews)

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HIT ID:HIT212667782
Cas No:
常用名:HS-PEG10-CH2CH2COOH
别名:Thiol-PEG10-propionic acid
IUPAC:1-sulfanyl-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oic acid
IUPAC:1-sulfanyl-3,6,9,12,15,18,21,24,27,30-decaoxatritriacontan-33-oic acid
InChI key:ZAWXZGPDQPXFEO-UHFFFAOYSA-N

分子式:C23H46O12S
分子量:546.67
氢键供体数 (HBD):2
氢键受体数 (HBA):12
LogP:-0.17787418
SMILES:OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCS
SMILES:OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCS

HS-PEG10-CH2CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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