Name: m-PEG24-acid
Rating: 5 (10 reviews)

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HIT ID:HIT212667868
Cas No:2248203-61-2
常用名:m-PEG24-acid
IUPAC:2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71-tetracosaoxatetraheptacontan-74-oic acid
IUPAC:2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71-tetracosaoxatetraheptacontan-74-oic acid
InChI key:DLRHQDPWEDMSOU-UHFFFAOYSA-N

分子式:C50H100O26
分子量:1117.324
氢键供体数 (HBD):1
氢键受体数 (HBA):26
LogP:-6.63
SMILES:COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
SMILES:COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O

m-PEG24-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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