Name: m-PEG5-triethoxysilane
Rating: 5 (10 reviews)

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HIT ID:HIT212667896
Cas No:2243566-42-7
常用名:m-PEG5-triethoxysilane
IUPAC:N-[3-(triethoxysilyl)propyl]-2,5,8,11,14-pentaoxaheptadecan-17-amide
IUPAC:N-[3-(triethoxysilyl)propyl]-2,5,8,11,14-pentaoxaheptadecan-17-amide
InChI key:RXDVHXFXNJERJZ-UHFFFAOYSA-N

分子式:C21H45NO9Si
分子量:483.674
氢键供体数 (HBD):1
氢键受体数 (HBA):9
LogP:-0.0382
SMILES:CCO[Si](CCCNC(=O)CCOCCOCCOCCOCCOC)(OCC)OCC
SMILES:CCO[Si](CCCNC(=O)CCOCCOCCOCCOCCOC)(OCC)OCC

m-PEG5-triethoxysilane is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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