Name: m-PEG7-Hydrazide
Rating: 5 (10 reviews)

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HIT ID:HIT212667901
Cas No:
常用名:m-PEG7-Hydrazide
IUPAC:2,5,8,11,14,17,20-heptaoxatricosane-23-hydrazide
IUPAC:2,5,8,11,14,17,20-heptaoxatricosane-23-hydrazide
InChI key:AZDFEGXVKDHLQO-UHFFFAOYSA-N

分子式:C16H34N2O8
分子量:382.454
氢键供体数 (HBD):2
氢键受体数 (HBA):9
LogP:-1.5457258
SMILES:COCCOCCOCCOCCOCCOCCOCCC(=O)NN
SMILES:COCCOCCOCCOCCOCCOCCOCCC(=O)NN

m-PEG7-Hydrazide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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