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HIT212667968
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HIT212667968
  • HIT ID:HIT212667968
  • Cas No:113387-03-4
  • 常用名:Mal-PEG5-mal
  • IUPAC:1-[17-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15-pentaoxaheptadecan-1-yl]-2,5-dihydro-1H-pyrrole-2,5-dione
    IUPAC:1-[17-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3,6,9,12,15-pentaoxaheptadecan-1-yl]-2,5-dihydro-1H-pyrrole-2,5-dione
  • InChI key:DDMVLALITLUWEX-UHFFFAOYSA-N
  • 分子式:C20H28N2O9
  • 分子量:440.449
  • 氢键供体数 (HBD):0
  • 氢键受体数 (HBA):9
  • LogP:-1.2308562
  • SMILES:O=C1C=CC(=O)N1CCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O |c:2,28|
    SMILES:O=C1C=CC(=O)N1CCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O |c:2,28|
  • Mal-PEG5-mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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