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HIT212667970
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HIT212667970
  • HIT ID:HIT212667970
  • Cas No:2353409-63-7
  • 常用名:Mal-PEG8-alcohol
  • IUPAC:1-(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricosan-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
    IUPAC:1-(23-hydroxy-3,6,9,12,15,18,21-heptaoxatricosan-1-yl)-2,5-dihydro-1H-pyrrole-2,5-dione
  • InChI key:ZIBIVFVJWRNGNY-UHFFFAOYSA-N
  • 分子式:C20H35NO10
  • 分子量:449.497
  • 氢键供体数 (HBD):1
  • 氢键受体数 (HBA):10
  • LogP:-1.4311575
  • SMILES:OCCOCCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O |c:27|
    SMILES:OCCOCCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O |c:27|
  • Mal-PEG8-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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