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HIT212668059
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HIT212668059
  • HIT ID:HIT212668059
  • Cas No:2055023-35-1
  • 常用名:N-Boc-N-bis(PEG3-acid)
  • IUPAC:3-(2-{2-[2-(16-carboxy-2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-5-yl)ethoxy]ethoxy}ethoxy)propanoic acid
    IUPAC:3-(2-{2-[2-(16-carboxy-2,2-dimethyl-4-oxo-3,8,11,14-tetraoxa-5-azahexadecan-5-yl)ethoxy]ethoxy}ethoxy)propanoic acid
  • InChI key:HVRLCVIGYIBUGD-UHFFFAOYSA-N
  • 分子式:C23H43NO12
  • 分子量:525.592
  • 氢键供体数 (HBD):2
  • 氢键受体数 (HBA):11
  • LogP:0.23845363
  • SMILES:CC(C)(C)OC(=O)N(CCOCCOCCOCCC(O)=O)CCOCCOCCOCCC(O)=O
    SMILES:CC(C)(C)OC(=O)N(CCOCCOCCOCCC(O)=O)CCOCCOCCOCCC(O)=O
  • N-Boc-N-bis(PEG3-acid) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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