Name: PEG20-Tos
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212668184
Cas No:2179113-08-5
常用名:PEG20-Tos
IUPAC:59-[(4-methylbenzenesulfonyl)oxy]-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57-nonadecaoxanonapentacontan-1-ol
IUPAC:59-[(4-methylbenzenesulfonyl)oxy]-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57-nonadecaoxanonapentacontan-1-ol
InChI key:ZWCZGEMXBISIJU-UHFFFAOYSA-N

分子式:C47H88O23S
分子量:1053.26
氢键供体数 (HBD):1
氢键受体数 (HBA):22
LogP:0.462898
SMILES:Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO
SMILES:Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

PEG20-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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