Name: Propargyl-PEG14-Boc
Rating: 5 (10 reviews)

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HIT ID:HIT212668223
Cas No:2055104-86-2
常用名:Propargyl-PEG14-Boc
IUPAC:tert-butyl 4,7,10,13,16,19,22,25,28,31,34,37,40,43-tetradecaoxahexatetracont-45-ynoate
IUPAC:tert-butyl 4,7,10,13,16,19,22,25,28,31,34,37,40,43-tetradecaoxahexatetracont-45-ynoate
InChI key:ZARGKRMZKKFQJH-UHFFFAOYSA-N

分子式:C36H68O16
分子量:756.924
氢键供体数 (HBD):0
氢键受体数 (HBA):15
LogP:0.6568006
SMILES:CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C
SMILES:CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C

Propargyl-PEG14-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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