Name: Propargyl-PEG8-SH
Rating: 5 (10 reviews)

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HIT ID:HIT212668240
Cas No:1422540-92-8
常用名:Propargyl-PEG8-SH
IUPAC:3,6,9,12,15,18,21,24-octaoxaheptacos-26-yne-1-thiol
IUPAC:3,6,9,12,15,18,21,24-octaoxaheptacos-26-yne-1-thiol
InChI key:IBJAGHUIGLSWBY-UHFFFAOYSA-N

分子式:C19H36O8S
分子量:424.55
氢键供体数 (HBD):1
氢键受体数 (HBA):8
LogP:0.42916384
SMILES:SCCOCCOCCOCCOCCOCCOCCOCCOCC#C
SMILES:SCCOCCOCCOCCOCCOCCOCCOCCOCC#C

Propargyl-PEG8-SH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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