Name: TCO-SS-amine
Rating: 5 (10 reviews)

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HIT ID:HIT212668415
Cas No:2918774-85-1
常用名:TCO-SS-amine
IUPAC:(1S,4E)-cyclooct-4-en-1-yl N-{2-[(2-aminoethyl)disulfanyl]ethyl}carbamate
IUPAC:(1S,4E)-cyclooct-4-en-1-yl N-{2-[(2-aminoethyl)disulfanyl]ethyl}carbamate
InChI key:OFLXMCDIPGWICF-YYRQZUAOSA-N

分子式:C13H24N2O2S2
分子量:304.47
氢键供体数 (HBD):2
氢键受体数 (HBA):2
LogP:2.0118606
SMILES:NCCSSCCNC(=O)O[C@H]1CCC\C=C\CC1 |t:15|
SMILES:NCCSSCCNC(=O)O[C@H]1CCC\C=C\CC1 |t:15|

TCO-SS-amine is a cleavable linker vital in ADC synthesis. TCO-SS-amine joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness.

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