Name: Azido-PEG3-maleimide
Rating: 5 (10 reviews)

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HIT ID:HIT212668614
Cas No:1858264-36-4
常用名:Azido-PEG3-maleimide
IUPAC:N-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide
IUPAC:N-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethyl)-3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide
InChI key:OGSSEPXEBBNVGN-UHFFFAOYSA-N

分子式:C15H23N5O6
分子量:369.378
氢键供体数 (HBD):1
氢键受体数 (HBA):8
LogP:-1.2911814
SMILES:[N-]=[N+]=NCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O |c:22|
SMILES:[N-]=[N+]=NCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O |c:22|

Azido-PEG3-maleimide is a PEG-based PROTAC linker primarily used for the synthesis of PROTACs[1]. Additionally, it serves as a cleavable 3-unit PEG ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[2].

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