Name: Benzyl-PEG2-CH2-Boc
Rating: 5 (10 reviews)

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HIT ID:HIT212668668
Cas No:1643957-26-9
常用名:Benzyl-PEG2-CH2-Boc
IUPAC:tert-butyl 2-{2-[2-(benzyloxy)ethoxy]ethoxy}acetate
IUPAC:tert-butyl 2-{2-[2-(benzyloxy)ethoxy]ethoxy}acetate
InChI key:IGVRCUZLYJDPKK-UHFFFAOYSA-N

分子式:C17H26O5
分子量:310.39
氢键供体数 (HBD):0
氢键受体数 (HBA):4
LogP:2.4329085
SMILES:CC(C)(C)OC(=O)COCCOCCOCc1ccccc1
SMILES:CC(C)(C)OC(=O)COCCOCCOCc1ccccc1

Benzyl-PEG2-CH2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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