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HIT212668689
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HIT212668689
  • HIT ID:HIT212668689
  • Cas No:1786206-22-1
  • 常用名:Biotin-PEG3-oxyamine
  • IUPAC:N-[2-(2-{2-[2-(aminooxy)ethoxy]ethoxy}ethoxy)ethyl]-5-{2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl}pentanamide
    IUPAC:N-[2-(2-{2-[2-(aminooxy)ethoxy]ethoxy}ethoxy)ethyl]-5-{2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl}pentanamide
  • InChI key:OLCOSDGJNTXSBD-UHFFFAOYSA-N
  • 分子式:C18H34N4O6S
  • 分子量:434.55
  • 氢键供体数 (HBD):5
  • 氢键受体数 (HBA):6
  • LogP:1.16
  • SMILES:NOCCOCCOCCOCCNC(=O)CCCCC1SCC2NC(=O)NC12
    SMILES:NOCCOCCOCCOCCNC(=O)CCCCC1SCC2NC(=O)NC12
  • Biotin-PEG3-oxyamine is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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