Name: Boc-Aminooxy-PEG3-acid
Rating: 5 (10 reviews)

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HIT ID:HIT212668735
Cas No:1835759-82-4
常用名:Boc-Aminooxy-PEG3-acid
IUPAC:1-{[(tert-butoxy)carbonyl]amino}-1,4,7,10-tetraoxatridecan-13-oic acid
IUPAC:1-{[(tert-butoxy)carbonyl]amino}-1,4,7,10-tetraoxatridecan-13-oic acid
InChI key:FRMJMYYWQYLTQT-UHFFFAOYSA-N

分子式:C14H27NO8
分子量:337.369
氢键供体数 (HBD):2
氢键受体数 (HBA):7
LogP:0.59181094
SMILES:CC(C)(C)OC(=O)NOCCOCCOCCOCCC(O)=O
SMILES:CC(C)(C)OC(=O)NOCCOCCOCCOCCC(O)=O

Boc-Aminooxy-PEG3-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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