Name: Bromoacetamido-C2-PEG2-NH-Boc
Rating: 5 (10 reviews)

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HIT ID:HIT212668789
Cas No:182244-33-3
常用名:Bromoacetamido-C2-PEG2-NH-Boc
IUPAC:tert-butyl N-(2-{2-[2-(2-bromoacetamido)ethoxy]ethoxy}ethyl)carbamate
IUPAC:tert-butyl N-(2-{2-[2-(2-bromoacetamido)ethoxy]ethoxy}ethyl)carbamate
InChI key:BLSNVTJXXUWHQT-UHFFFAOYSA-N

分子式:C13H25BrN2O5
分子量:369.256
氢键供体数 (HBD):2
氢键受体数 (HBA):4
LogP:0.51738936
SMILES:CC(C)(C)OC(=O)NCCOCCOCCNC(=O)CBr
SMILES:CC(C)(C)OC(=O)NCCOCCOCCNC(=O)CBr

Bromoacetamido-C2-PEG2-NH-Boc is a polyethylene glycol (PEG)-based linker with a bromoacetamido functional group and a tert-butoxycarbonyl (Boc) protecting group. It serves as an integral component in the synthesis of proteolysis-targeting chimeras (PROTACs), which are innovative compounds used for targeted protein degradation[1].

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