Name: Methylamino-PEG4-Boc
Rating: 5 (10 reviews)

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HIT ID:HIT212669027
Cas No:1621616-14-5
常用名:Methylamino-PEG4-Boc
别名:Methylamino-PEG4-t-butyl ester
IUPAC:tert-butyl 5,8,11,14-tetraoxa-2-azaheptadecan-17-oate
IUPAC:tert-butyl 5,8,11,14-tetraoxa-2-azaheptadecan-17-oate
InChI key:ZNZXARLRHZPMJU-UHFFFAOYSA-N

分子式:C16H33NO6
分子量:335.441
氢键供体数 (HBD):1
氢键受体数 (HBA):6
LogP:0.53406924
SMILES:CNCCOCCOCCOCCOCCC(=O)OC(C)(C)C
SMILES:CNCCOCCOCCOCCOCCC(=O)OC(C)(C)C

Methylamino-PEG4-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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