Name: N-Boc-N-bis-PEG5
Rating: 5 (10 reviews)

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HIT ID:HIT212669083
Cas No:2093154-02-8
常用名:N-Boc-N-bis-PEG5
IUPAC:tert-butyl N,N-bis(14-hydroxy-3,6,9,12-tetraoxatetradecan-1-yl)carbamate
IUPAC:tert-butyl N,N-bis(14-hydroxy-3,6,9,12-tetraoxatetradecan-1-yl)carbamate
InChI key:ORLQQCLGZAXNLD-UHFFFAOYSA-N

分子式:C25H51NO12
分子量:557.678
氢键供体数 (HBD):2
氢键受体数 (HBA):11
LogP:-0.6656935
SMILES:CC(C)(C)OC(=O)N(CCOCCOCCOCCOCCO)CCOCCOCCOCCOCCO
SMILES:CC(C)(C)OC(=O)N(CCOCCOCCOCCOCCO)CCOCCOCCOCCOCCO

N-Boc-N-bis-PEG5 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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