Name: NH-bis-PEG5
Rating: 5 (10 reviews)

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HIT ID:HIT212669134
Cas No:63721-06-2
常用名:NH-bis-PEG5
IUPAC:3,6,9,12,18,21,24,27-octaoxa-15-azanonacosane-1,29-diol
IUPAC:3,6,9,12,18,21,24,27-octaoxa-15-azanonacosane-1,29-diol
InChI key:IDUORIHIPQGGGX-UHFFFAOYSA-N

分子式:C20H43NO10
分子量:457.561
氢键供体数 (HBD):3
氢键受体数 (HBA):11
LogP:-1.9488865
SMILES:OCCOCCOCCOCCOCCNCCOCCOCCOCCOCCO
SMILES:OCCOCCOCCOCCOCCNCCOCCOCCOCCOCCO

NH-bis-PEG5 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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