Name: Propargyl-PEG9-OH
Rating: 5 (10 reviews)

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HIT ID:HIT212669205
Cas No:2055022-35-8
常用名:Propargyl-PEG9-OH
IUPAC:3,6,9,12,15,18,21,24,27-nonaoxatriacont-29-yn-1-ol
IUPAC:3,6,9,12,15,18,21,24,27-nonaoxatriacont-29-yn-1-ol
InChI key:FBQGPFAGZKPHQT-UHFFFAOYSA-N

分子式:C21H40O10
分子量:452.541
氢键供体数 (HBD):1
氢键受体数 (HBA):10
LogP:-0.7132736
SMILES:OCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C
SMILES:OCCOCCOCCOCCOCCOCCOCCOCCOCCOCC#C

Propargyl-PEG9-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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