Name: Tos-PEG2-CH2COOH
Rating: 5 (10 reviews)

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HIT ID:HIT212669262
Cas No:1807537-35-4
常用名:Tos-PEG2-CH2COOH
IUPAC:2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)acetic acid
IUPAC:2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)acetic acid
InChI key:QQHWSZBWDYTXGD-UHFFFAOYSA-N

分子式:C13H18O7S
分子量:318.34
氢键供体数 (HBD):1
氢键受体数 (HBA):6
LogP:1.429567
SMILES:Cc1ccc(cc1)S(=O)(=O)OCCOCCOCC(O)=O
SMILES:Cc1ccc(cc1)S(=O)(=O)OCCOCCOCC(O)=O

Tos-PEG2-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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