Name: Tos-PEG3-CH2COOH
Rating: 5 (10 reviews)

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HIT ID:HIT212669266
Cas No:1581248-63-6
常用名:Tos-PEG3-CH2COOH
IUPAC:2-[2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)ethoxy]acetic acid
IUPAC:2-[2-(2-{2-[(4-methylbenzenesulfonyl)oxy]ethoxy}ethoxy)ethoxy]acetic acid
InChI key:BOUJNGOUZPSTFF-UHFFFAOYSA-N

分子式:C15H22O8S
分子量:362.39
氢键供体数 (HBD):1
氢键受体数 (HBA):7
LogP:1.3825915
SMILES:Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCC(O)=O
SMILES:Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCC(O)=O

Tos-PEG3-CH2COOH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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