Name: Tos-PEG7-OH
Rating: 5 (10 reviews)

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HIT ID:HIT212669271
Cas No:1028089-05-5
常用名:Tos-PEG7-OH
IUPAC:20-[(4-methylbenzenesulfonyl)oxy]-3,6,9,12,15,18-hexaoxaicosan-1-ol
IUPAC:20-[(4-methylbenzenesulfonyl)oxy]-3,6,9,12,15,18-hexaoxaicosan-1-ol
InChI key:OPGOVMSKPDWRRQ-UHFFFAOYSA-N

分子式:C21H36O10S
分子量:480.57
氢键供体数 (HBD):1
氢键受体数 (HBA):9
LogP:1.0735795
SMILES:Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCO
SMILES:Cc1ccc(cc1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCO

Tos-PEG7-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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