Name: Trityl-PEG8-azide
Rating: 5 (10 reviews)

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HIT ID:HIT212669278
Cas No:1818294-30-2
常用名:Trityl-PEG8-azide
IUPAC:25-azido-1,1,1-triphenyl-2,5,8,11,14,17,20,23-octaoxapentacosane
IUPAC:25-azido-1,1,1-triphenyl-2,5,8,11,14,17,20,23-octaoxapentacosane
InChI key:GMEFSMLZCBKWDL-UHFFFAOYSA-N

分子式:C35H47N3O8
分子量:637.774
氢键供体数 (HBD):0
氢键受体数 (HBA):10
LogP:5.0829186
SMILES:[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOC(c1ccccc1)(c1ccccc1)c1ccccc1
SMILES:[N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOC(c1ccccc1)(c1ccccc1)c1ccccc1

Trityl-PEG8-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

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