Name: Amelubant
Rating: 5 (10 reviews)

有库存

sdf 文件

结构编辑

类似物检索

HIT ID:HIT212669323
Cas No:346735-24-8
常用名:Amelubant
别名:BIIL 284
IUPAC:ethyl N-(4-{[3-({4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy}methyl)phenyl]methoxy}benzenecarboximidoyl)carbamate
IUPAC:ethyl N-(4-{[3-({4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy}methyl)phenyl]methoxy}benzenecarboximidoyl)carbamate
InChI key:SBVYURPQULDJTI-UHFFFAOYSA-N

分子式:C33H34N2O5
分子量:538.644
氢键供体数 (HBD):3
氢键受体数 (HBA):5
LogP:7.3101535
SMILES:CCOC(=O)NC(=N)c1ccc(OCc2cccc(COc3ccc(cc3)C(C)(C)c3ccc(O)cc3)c2)cc1
SMILES:CCOC(=O)NC(=N)c1ccc(OCc2cccc(COc3ccc(cc3)C(C)(C)c3ccc(O)cc3)c2)cc1

Amelubant (BIIL 284) is a prodrug of active metabolites BIIL 260 and BIIL 315 with anti-inflammatory activity[1]. It is a potent, oral, long-acting LTB4 receptor antagonist that negligibly binds to the LTB4 receptor, exhibiting Kis of 221 nM and 230 nM in vital cells and membranes.

市场产品/服务共显示1个结果

您无法确定哪种化合物库最适合您的项目？或者您需要定制解决方案？Anymole随时为您提供帮助。

电话：400820-0310

合作：info@screeningcompound.com

技术支持：tech@screeningcompound.com

客服：service@screeningcompound.com

正在加载 ~